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OncoMatch/Clinical Trials/NCT06626230

Safety of Anal Curcumin

Is NCT06626230 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies Curcuminoid Capsules for anal high grade squamous intraepithelial lesion.

Phase 1RecruitingLisa FlowersNCT06626230Data as of May 2026

Treatment: Curcuminoid CapsulesThe purpose of this study is to see if curcumin can reverse anal high-grade squamous intraepithelial lesions (aHSIL) (high-grade anal precancerous cells or high-grade abnormal cells) in people living with HIV to avoid current treatments such as ablation (destroying abnormal cells with heat or surgical excision (cutting out the abnormal cells)), which have potential short- and long-term side effects.

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Extracted eligibility criteria

Prior therapy

No prior treatment (treatment-naive required)

Lab requirements

Blood counts

no grade 2 or higher hematology abnormality

Kidney function

no grade 2 or higher renal abnormality

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Grady Memorial Hospital · Atlanta, Georgia
  • Grady Hospital - Ponce De Leon Clinic · Atlanta, Georgia

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