OncoMatch

OncoMatch/Clinical Trials/NCT06615479

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Is NCT06615479 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies multiple treatments for relapsed or refractory multiple myeloma (rrmm).

Phase 3RecruitingJuno Therapeutics, Inc., a Bristol-Myers Squibb CompanyNCT06615479Data as of Jun 2026Location: International · 31 countries

Treatment: BMS-986393 · Cyclophosphamide · Fludarabine · Daratumumab · Pomalidomide · Dexamethasone · CarfilzomibThe purpose of this study is to compare the efficacy and safety of arlo-cel (BMS-986393) versus standard regimens in adult participants with Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma.

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Daratumumab

Targeted therapy

Carfilzomib

Chemotherapy

CyclophosphamideFludarabine

Endocrine / hormonal

Pomalidomide

Other

BMS-986393Dexamethasone

Cancer type

Multiple Myeloma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Max 3 prior lines
Min 1 prior line

Must have received: lenalidomide (lenalidomide)

Lab requirements

Blood counts

Kidney function

Liver function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Alabama at Birmingham · Birmingham, Alabama
  • UCLA Hematology/Oncology - Santa Monica · Los Angeles, California
  • Local Institution - 0050 · Orange, California
  • Local Institution - 0223 · Washington D.C., District of Columbia
  • Baptist MD Anderson Cancer Center · Jacksonville, Florida

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT06615479 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received lenalidomide.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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