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OncoMatch/Clinical Trials/NCT06615193

A Study of HDM2005 in Patients With Relapsed/Refractory B-cell Lymphoma and Advanced Solid Tumor

Is NCT06615193 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies HDM2005 for advanced solid tumors.

Phase 1RecruitingHangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.NCT06615193Data as of May 2026

Treatment: HDM2005This is a first-in-human (FIH) study to evaluate the safety and preliminary efficacy of experimental drug HDM2005 in patients with relapsed/refractory B-cell lymphoma and advanced solid tumors.

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Non-Hodgkin Lymphoma

Acute Myeloid Leukemia

Acute Lymphoblastic Leukemia

Multiple Myeloma

Myelodysplastic Syndrome

Chronic Lymphocytic Leukemia

Biomarker criteria

Required: ROR1 expression

ROR1 expression testing at the central laboratory

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Min 2 prior lines

Lab requirements

Blood counts

Kidney function

Liver function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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