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OncoMatch/Clinical Trials/NCT06613841

Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma

Is NCT06613841 recruiting? Yes, currently enrolling (May 2026). This Early Phase 1 trial studies Fluciclovine F18 for glioblastoma.

Early Phase 1RecruitingAbramson Cancer Center at Penn MedicineNCT06613841Data as of May 2026

Treatment: Fluciclovine F18* To perform metabolic phenotyping of treatment naïve and recurrent GBM by multitracer \[18F\]Fluciclovine and 18F-FDG PET. * To compare uptake measures of 18F-Fluciclovine and 18F-FDG and MRI quantification of glutamate and lactate levels to tumor tissue laboratory assays (RNA seq and proteomics) of glutamine/glutamate, glucose, and lactate metabolism. * To perform metabolic phenotyping of treatment naïve and recurrent GBM by advanced MRI methods at 7 Tesla

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Extracted eligibility criteria

Cancer type

Glioblastoma

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Hospital of the University of Pennsylvania · Philadelphia, Pennsylvania
  • University of Pennsylvania · Philadelphia, Pennsylvania

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