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OncoMatch/Clinical Trials/NCT06598787

A Study of BL-B01D1 in Patients With Recurrent Glioblastoma

Is NCT06598787 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies BL-B01D1 for for recurrent glioblastoma.

Phase 2RecruitingSichuan Baili Pharmaceutical Co., Ltd.NCT06598787Data as of May 2026

Treatment: BL-B01D1 forThis is an open-label, multicenter, phase II study to evaluate the safety, efficacy, and pharmacokinetic characteristics of BL-B01D1 for Injection in patients with recurrent glioblastoma.

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Extracted eligibility criteria

Cancer type

Glioblastoma

Prior therapy

Min 1 prior line

Must have received: standard treatment

Recurrent glioblastoma confirmed by pathology after failure of standard treatment

Cannot have received: chemotherapy, biological therapy, immunotherapy

Chemotherapy, biological therapy, immunotherapy, etc., had been used within 4 weeks or 5 half-lives before the first dose

Cannot have received: small molecule targeted therapy

small molecule targeted therapy had been used within 5 days

Cannot have received: palliative radiotherapy

palliative radiotherapy ... had been used within 2 weeks

Cannot have received: modern Chinese medicine preparations approved by NMPA for anti-tumor treatment

modern Chinese medicine preparations approved by NMPA for anti-tumor treatment had been used within 2 weeks

Lab requirements

Blood counts

No blood transfusion, albumin, colony-stimulating factor, any cell growth factor and/or platelet-raising drugs are allowed within 14 days before the first dose of study drug, and the organ function level must meet the requirements

Cardiac function

No severe cardiac dysfunction, left ventricular ejection fraction ≥50%

No severe cardiac dysfunction, left ventricular ejection fraction ≥50%; No blood transfusion, albumin, colony-stimulating factor, any cell growth factor and/or platelet-raising drugs are allowed within 14 days before the first dose of study drug, and the organ function level must meet the requirements

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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