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OncoMatch/Clinical Trials/NCT06593431

Extending Outcomes for Pancreas Cancer Patients With Nominal Oligometastatic Disease (EXPAND): A Randomized Phase III Trial

Is NCT06593431 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies non-drug interventions for pancreas cancer.

Phase 3RecruitingM.D. Anderson Cancer CenterNCT06593431Data as of Jun 2026

The EXPAND trial (EXtending outcomes for PAncreas cancer patients with Nominal oligometastatic Disease) is a randomized phase III trial assessing the efficacy of MDT to improve PFS and OS for patients with oligometastatic pancreatic ductal adenocarcinoma (PDAC).

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Extracted eligibility criteria

Cancer type

Pancreatic Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Max 4 prior lines

Lab requirements

Blood counts

Demonstration of adequate organ function as defined in the table below, all screening labs to be performed within 4 weeks prior to study enrollment

Kidney function

Demonstration of adequate organ function as defined in the table below, all screening labs to be performed within 4 weeks prior to study enrollment

Liver function

Demonstration of adequate organ function as defined in the table below, all screening labs to be performed within 4 weeks prior to study enrollment

Demonstration of adequate organ function as defined in the table below, all screening labs to be performed within 4 weeks prior to study enrollment

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT06593431 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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