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OncoMatch/Clinical Trials/NCT06593431

Extending Outcomes for Pancreas Cancer Patients With Nominal Oligometastatic Disease (EXPAND): A Randomized Phase III Trial

Is NCT06593431 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies non-drug interventions for pancreas cancer.

Phase 3RecruitingM.D. Anderson Cancer CenterNCT06593431Data as of May 2026

The EXPAND trial (EXtending outcomes for PAncreas cancer patients with Nominal oligometastatic Disease) is a randomized phase III trial assessing the efficacy of MDT to improve PFS and OS for patients with oligometastatic pancreatic ductal adenocarcinoma (PDAC).

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Extracted eligibility criteria

Cancer type

Pancreatic Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Max 4 prior lines

Lab requirements

Blood counts

Demonstration of adequate organ function as defined in the table below, all screening labs to be performed within 4 weeks prior to study enrollment

Kidney function

Demonstration of adequate organ function as defined in the table below, all screening labs to be performed within 4 weeks prior to study enrollment

Liver function

Demonstration of adequate organ function as defined in the table below, all screening labs to be performed within 4 weeks prior to study enrollment

Demonstration of adequate organ function as defined in the table below, all screening labs to be performed within 4 weeks prior to study enrollment

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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