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OncoMatch/Clinical Trials/NCT06591819

Hypofractionated WPPT With HDR Boost

Is NCT06591819 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for prostate cancer.

Phase 2RecruitingAbramson Cancer Center at Penn MedicineNCT06591819Data as of May 2026

This is a phase II study of ultrahypofractionated whole pelvis proton therapy with brachytherapy boost for patients with high risk or unfavorable intermediate risk prostate with elevated risk of lymph node involvement.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Required: Stage T2C

High risk: T3a or Gleason Grade Group 4/5 or PSA >20 Unfavorable intermediate risk disease: at least one or more of the following: T2b-T2c, Gleason Grade Group 2/3, PSA 10-20, >50% of cores positive

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: radiation therapy

No prior radiotherapy in the region of study

Cannot have received: radiation therapy

Prior radiation to the pelvis

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Pennsylvania · Philadelphia, Pennsylvania

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