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OncoMatch/Clinical Trials/NCT06587061

HRS-4642 in Combination With AG for Neoadjuvant and Adjuvant Treatment of Pancreatic Cancer

Is NCT06587061 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies HRS-4642+AG for pancreatic cancer.

Phase 2RecruitingRuijin HospitalNCT06587061Data as of Jun 2026Location: China

Treatment: HRS-4642+AGTo evaluate the safety and efficacy of HRS-4642 in Combination With AG for Neoadjuvant and Adjuvant Treatment of Pancreatic Cancer

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Extracted eligibility criteria

Treatments studied

Other

HRS-4642+AG

Cancer type

Pancreatic Cancer

Disease stage

Required: Stage RESECTABLE PANCREATIC CANCER (INCLUDING HIGH-RISK RESECTABLE), BORDERLINE RESECTABLE PANCREATIC CANCER (NCCN guidelines)

Excluded: Stage DISTANT METASTATIC

Imaging evaluation met the NCCN guidelines definition of resectable pancreatic cancer (including high-risk resectable) and borderline resectable pancreatic cancer. the presence of distant metastatic lesions diagnosed by imaging [excluded]

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 80

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: anti-tumor therapy

Previously received any anti-tumor therapy

Lab requirements

Blood counts

adequate marrow function

Kidney function

adequate organ function

Liver function

adequate organ function

Adequate marrow and organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06587061 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

What disease stage is eligible?

Stage RESECTABLE PANCREATIC CANCER (INCLUDING HIGH-RISK RESECTABLE) or BORDERLINE RESECTABLE PANCREATIC CANCER is required.

Is there an age limit?

Yes. Patients must be 80 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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