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OncoMatch/Clinical Trials/NCT06584006

Thymalfasin and Recombinant Human IL-2 Injections in Treating Lymphocytopenia for Patients With Malignant Hematological Tumors

Is NCT06584006 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Thymalfasin for and Recombinant Human Interleukin-2 Injections for hematological malignancy.

Phase 2RecruitingThe First Affiliated Hospital of Xiamen UniversityNCT06584006Data as of May 2026

Treatment: Thymalfasin for · Recombinant Human Interleukin-2 InjectionsTo evaluate the efficacy and safety of Thymalfasin for injection in combination with Recombinant Human Interleukin-2 Injections in the treatment of lymphocytopenia in patients with malignant hematological tumors

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Extracted eligibility criteria

Cancer type

Acute Myeloid Leukemia

Acute Lymphoblastic Leukemia

Non-Hodgkin Lymphoma

Multiple Myeloma

Myelodysplastic Syndrome

Chronic Lymphocytic Leukemia

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: chemotherapy

Within 8 days after chemotherapy for lymphoma and within 14 days after chemotherapy for AML

Cannot have received: immunosuppressive treatment (cyclosporine, corticosteroids, ruxolitinib, JAK1/2 inhibitors)

Immunosuppressive treatment (such as cyclosporine, corticosteroids, ruxolitinib, JAK1/2 inhibitors, etc.) within the past 5 days

Cannot have received: allogeneic hematopoietic stem cell transplantation

Patients who have undergone allogeneic hematopoietic stem cell transplantation

Lab requirements

Blood counts

Tumor involvement in the bone marrow leading to hematopoietic suppression (neutrophils <1.0×10^9/L, HB<70g/L, PLT<50×10^9/L) [excluded]

Kidney function

Estimated creatinine clearance rate ≥ 30 mL/min.

Liver function

AST and ALT ≤ 3.0 x ULN. Bilirubin ≤ 1.5 x ULN.

Estimated creatinine clearance rate ≥ 30 mL/min. AST and ALT ≤ 3.0 x ULN. Bilirubin ≤ 1.5 x ULN. Tumor involvement in the bone marrow leading to hematopoietic suppression (neutrophils <1.0×10^9/L, HB<70g/L, PLT<50×10^9/L) [excluded]

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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