OncoMatch/Clinical Trials/NCT06579248
Intraoral Hypothermia Device for Preserving Taste During Radiation
Is NCT06579248 recruiting? Yes, currently enrolling (May 2026). This Early Phase 1 trial studies Intraoral Device for head and neck cancer.
Treatment: Intraoral Device — Radiation therapy to the head and neck region is known to cause taste dysfunction. Preliminary studies showed that cooling normal structures may lower damage caused by radiation. The purpose of this research study is to see if it is feasible to use an intraoral cooling device during radiation treatments to preserve or lower the decline of taste function.
Check if I qualifyExtracted eligibility criteria
Cancer type
Head and Neck Squamous Cell Carcinoma
Disease stage
Required: Stage AJCC 8TH CT3, AJCC 8TH CT4, AJCC 8TH CN+ (AJCC 8th)
locally advanced (AJCC 8th cT3-4 or cN+)
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Cannot have received: chemotherapy
Cannot have received: radiation therapy
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Henry Ford Health System · Detroit, Michigan
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