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OncoMatch/Clinical Trials/NCT06563388

Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial

Is NCT06563388 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies non-drug interventions for oligometastasis.

Phase 3RecruitingRoswell Park Cancer InstituteNCT06563388Data as of May 2026

This protocol is comprised of three unblinded, randomized, single-center studies to evaluate the impact of immediate versus three-month delayed comprehensive ablative treatment on survival in newly diagnosed metastatic patients with lung (Trial 1), colorectal (Trial 2), and prostate (Trial 3) cancers

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Colorectal Cancer

Prostate Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–3(Limited self-care)

Prior therapy

Cannot have received: chemotherapy

Exception: allowed if completed >3 weeks prior to study entry (6 weeks for nitrosoureas or mitomycin C) and recovered from adverse events

Participants who have had chemotherapy or radiotherapy within 3 weeks (6 weeks for nitrosoureas or mitomycin C) prior to entering the study or those who have not recovered from adverse events due to agents administered more than 3 weeks earlier

Cannot have received: radiotherapy

Exception: allowed if completed >3 weeks prior to study entry (6 weeks for nitrosoureas or mitomycin C) and recovered from adverse events; prior radiotherapy in general is allowed, as long as the composite plan meets dose constraints

Participants who have had chemotherapy or radiotherapy within 3 weeks (6 weeks for nitrosoureas or mitomycin C) prior to entering the study or those who have not recovered from adverse events due to agents administered more than 3 weeks earlier. Prior radiotherapy in general is allowed, as long as the composite plan meets dose constraints herein.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Roswell Park Comprehensive Cancer Center · Buffalo, New York

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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