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OncoMatch/Clinical Trials/NCT06558981

Adjuvant Radiotherapy in High Risk Locally Advanced DTC

Is NCT06558981 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies non-drug interventions for thyroid cancer.

Phase 3RecruitingFudan UniversityNCT06558981Data as of Jun 2026Location: China

This study is a phase III randomized controlled clinical trial on the role of adjuvant radiotherapy in high-risk locally advanced differentiated thyroid cancer. Patients who meet the inclusion criteria were randomly assigned 1:1 to either the experimental group (adjuvant radiotherapy+RAI) or the control group (RAI), with LRFS as the primary endpoint of the study.

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Demographics

Ages 14–80

Prior therapy

Must have received: surgical total or near total thyroidectomy

Surgical total or near total thyroidectomy

Cannot have received: radiation therapy for the head and neck area

Previously received radiation therapy for the head and neck area

Cannot have received: radioiodine (131I)

Previously received 131I treatment

Cannot have received: targeted therapy

Previously received or currently receiving targeted therapy

Cannot have received: immunotherapy

Previously received or currently receiving immunotherapy

Cannot have received: chemotherapy

Previously received or currently receiving chemotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06558981 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior radiation therapy for the head and neck area, radioiodine, targeted therapy disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 80 years or younger and at least 14 years old.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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