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OncoMatch/Clinical Trials/NCT06558227

Study of ZG005 Combined With Bevacizumab Versus Sintilimab Combined With Bevacizumab in Advanced Hepatocellular Carcinoma

Is NCT06558227 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including ZG005 for and Bevacizumab for hepatocellular carcinoma.

Phase 2RecruitingSuzhou Zelgen Biopharmaceuticals Co.,LtdNCT06558227Data as of Jun 2026Location: China

Treatment: ZG005 for · Bevacizumab · Sintilimab · BevacizumabThis study is a randomized, open-label, positive-controlled, multicenter phase II clinical trial. It evaluates the efficacy and safety of ZG005 combined with Bevacizumab compared to Sintilimab combined with Bevacizumab in first-line treatment for patients with advanced hepatocellular carcinoma.

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Sintilimab

Targeted therapy

BevacizumabBevacizumab

Other

ZG005 for

Cancer type

Hepatocellular Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06558227 currently recruiting?

Yes, this trial is currently recruiting patients.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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