OncoMatch/Clinical Trials/NCT06549595
A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients
Is NCT06549595 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies multiple treatments including Surovatamig and R-CHOP for untreated follicular lymphoma.
Treatment: Surovatamig · R-CHOP · R-CVP · BR — This is a global, randomised, Phase III, multicentre, open-label study evaluating the efficacy, safety and the degree of added benefit of the Surovatamig (AZD0486) plus rituximab combination compared to Investigator's choice of 3 standard immunochemotherapy regimen, conducted in participants with untreated FL.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Non-Hodgkin Lymphoma
Disease stage
Required: Stage II, III, IV
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Demographics
Prior therapy
Lab requirements
Blood counts
adequate hematological function
Kidney function
adequate renal function
Liver function
adequate liver function
Cardiac function
adequate cardiac function
Adequate liver, hematological, renal and cardiac function.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Research Site · Anchorage, Alaska
- Research Site · Aurora, Colorado
- Research Site · New Haven, Connecticut
- Research Site · Ann Arbor, Michigan
- Research Site · New York, New York
Showing up to 5 US sites.
See all sites on ClinicalTrials.gov →Frequently asked questions
Is NCT06549595 currently recruiting?
Yes, this trial is currently recruiting patients.
Can patients have received prior systemic therapy?
No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.
What disease stage is eligible?
Stage II or III or IV is required.
Is there an age limit?
Yes. Patients must be 130 years or younger.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages