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OncoMatch/Clinical Trials/NCT06537843

Safety and Efficacy of Venetoclax, Cytarabine and Metformin (VenCM) for Relapsed-Refractory and Induction-Ineligible Acute Myeloid Leukemia

Is NCT06537843 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Venetoclax and Cytarabine for acute myeloid leukemia.

Phase 2RecruitingHospital Municipal São JoséNCT06537843Data as of Jun 2026Location: Brazil

Treatment: Venetoclax · Cytarabine · MetforminPhase 2 clinical trial to evaluate the combination of venetoclax, cytarabine and metformin in relapsed-refractory and induction ineligible acute myeloid leukemia.

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Extracted eligibility criteria

Treatments studied

Targeted therapy

Venetoclax

Chemotherapy

Cytarabine

Other

Metformin

Cancer type

Acute Myeloid Leukemia

Performance status

ECOG 2–3(Limited self-care)

Lab requirements

Kidney function

creatinine clearance below 60 mL/min/1,73m²

Cardiac function

left ventricular ejection fraction ≤ 50%

creatinine clearance below 60 mL/min/1,73m², left ventricular ejection fraction ≤ 50%

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06537843 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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