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OncoMatch/Clinical Trials/NCT06523621

Nivolumab in Multiple Myeloma Patients After Idecabtagene Vicleucel

Is NCT06523621 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Nivolumab for multiple myeloma.

Phase 2RecruitingWake Forest University Health SciencesNCT06523621Data as of May 2026

Treatment: NivolumabThis study is designed to evaluate if treatment with adjuvant nivolumab improves depth of response in patients with relapsed refractory multiple myeloma (RRMM) who achieve a less-than-ideal response to idecaptagene vicleucel.

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Extracted eligibility criteria

Cancer type

Multiple Myeloma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 1 prior line

Must have received: CAR-T cell therapy (idecabtagene vicleucel) — per FDA approved US prescribing information

Previous treatment with idecabtagene vicleucel according to the FDA approved US prescribing information with a response of CR/sCR, VGPR or PR by IMWG 2016 criteria

Cannot have received: autologous stem cell transplant

Exception: allowed if >12 weeks before C1D1

Autologous stem cell transplant within 12 weeks of C1D1

Cannot have received: allogeneic stem cell transplant

Allogeneic stem cell transplant

Cannot have received: solid organ transplant

Solid organ transplant

Lab requirements

Blood counts

Demonstrate adequate organ function as defined in the table below; all screening labs to be obtained within 28 days prior to enrollment.

Kidney function

Demonstrate adequate organ function as defined in the table below; all screening labs to be obtained within 28 days prior to enrollment.

Liver function

Demonstrate adequate organ function as defined in the table below; all screening labs to be obtained within 28 days prior to enrollment.

Demonstrate adequate organ function as defined in the table below; all screening labs to be obtained within 28 days prior to enrollment.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Levine Cancer Institute · Charlotte, North Carolina
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center · Winston-Salem, North Carolina

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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