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OncoMatch/Clinical Trials/NCT06517017

Use of Isatuximab, Dexamethasone and Lenalidomide in a Go-Slow Fashion for Ultra-Frail Patients With Multiple Myeloma

Is NCT06517017 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Isatuximab for multiple myeloma.

Phase 2RecruitingUniversity of UtahNCT06517017Data as of Jun 2026

Treatment: IsatuximabHistorically, the frailest patients with multiple myeloma are under-represented in clinical trials, and have very high rates of treatment discontinuation, and early treatment mortality. The investigators hypothesize that a go-slow gentle approach to starting treatment in such patients, starting with just Isatuximab and dexamethasone with a gentle introduction to lenalidomide third cycle onwards, may improve treatment adherence and quality of life. The goal of this clinical trial is to learn if a go-slow approach to treating MM in ultra-frail patients may improve the ability to adhere to treatment and improve quality of life.

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Isatuximab

Cancer type

Multiple Myeloma

Prior therapy

Max 1 prior line

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Huntsman Cancer Institute at the University of Utah · Salt Lake City, Utah

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Frequently asked questions

Is NCT06517017 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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