OncoMatch

OncoMatch/Clinical Trials/NCT06514794

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

Is NCT06514794 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies WU-CART-007 for t-cell acute lymphoblastic leukemia.

Phase 2RecruitingWugen, Inc.NCT06514794Data as of May 2026

Treatment: WU-CART-007The T-RRex study evaluates the efficacy of WU-CART-007 for patients with Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL)/Lymphoblastic Lymphoma (LBL) and to WU-CART-007 as a therapy to induce complete Minimum Residual Disease (MRD) negative response

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Extracted eligibility criteria

Cancer type

Acute Lymphoblastic Leukemia

Non-Hodgkin Lymphoma

Performance status

ECOG/KARNOFSKY 0–1

Prior therapy

Cannot have received: anti-CD7 therapy

Prior treatment with any anti-CD7 therapy.

Lab requirements

Blood counts

adequate organ function

Kidney function

adequate organ function

Liver function

adequate organ function

adequate organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • City of Hope · Duarte, California
  • Children's Hospital Los Angeles · Los Angeles, California
  • H. Lee Moffitt Cancer Center and Research Institute Hospital · Tampa, Florida
  • Washington University Saint Louis · St Louis, Missouri
  • Cincinnati Children's Hospital Medical Center · Cincinnati, Ohio

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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