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OncoMatch/Clinical Trials/NCT06511037

PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomatosis

Is NCT06511037 recruiting? Yes, currently enrolling (May 2026). This Early Phase 1 trial studies Pafolacianine (CYTALUX) with intraoperative fluorescent near-infrared (NIR) imaging for gastrointestinal cancer.

Early Phase 1RecruitingUniversity of California, IrvineNCT06511037Data as of May 2026

Treatment: Pafolacianine (CYTALUX) with intraoperative fluorescent near-infrared (NIR) imagingThis is a pilot, single-arm, open label study to evaluate the ability of CYTALUX™ (pafolacianine) to help identify cancerous lesions in subjects with gastrointestinal cancers and peritoneal carcinomatosis during cytoreductive surgery.

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Extracted eligibility criteria

Cancer type

Colorectal Cancer

Gastric Cancer

Hepatocellular Carcinoma

Pancreatic Cancer

Cholangiocarcinoma

Esophageal Carcinoma

Ovarian Cancer

Prior therapy

Cannot have received: pafolacianine (cytalux, pafolacianine)

Cannot have received: investigational agent

Lab requirements

Kidney function

eGFR <50 mL/min/1.73m2 excluded

Liver function

ALT, AST, ALP, or total bilirubin >3x ULN excluded

Impaired renal function defined as eGFR <50 mL/min/1.73m2; Impaired liver function defined as values >3x the upper limit of normal (ULN) for alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), or total bilirubin; Clinically significant abnormalities on ECG

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Chao Family Comprehensive Cancer Center, University of California, Irvine · Orange, California

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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