OncoMatch

OncoMatch/Clinical Trials/NCT06510660

Adebrelimab ±Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC

Is NCT06510660 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies adebrelimab for esophageal squamous cell carcinoma.

Phase 2RecruitingFujian Medical University Union HospitalNCT06510660Data as of Jun 2026Location: China

Treatment: adebrelimabTo evaluate the efficacy and safety of adebrelimab with or without induction chemotherapy followed by concurrent chemoradiotherapy for unresectable locally advanced esophageal squamous cell carcinoma

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Extracted eligibility criteria

Treatments studied

Immunotherapy

adebrelimab

Cancer type

Esophageal Carcinoma

Disease stage

Required: Stage II, III, IVA, IVB

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 70

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: immunotherapy

Prior treatment with immunotherapy

Lab requirements

Blood counts

Kidney function

Liver function

Adequate organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06510660 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

What disease stage is eligible?

Stage II or III or IVA or IVB is required.

Is there an age limit?

Yes. Patients must be 70 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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