OncoMatch/Clinical Trials/NCT06508099
Vitamin A and D Supplementation in Allogeneic HCT
Is NCT06508099 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Vitamin A and Vitamin D3 for acute lymphoblastic leukemia.
Treatment: Vitamin A · Vitamin D3 — The therapy under investigation is the addition of 300 000 IU of vitamin A and 100 000 IU of vitamin D before conditioning. The study will include patients with malignant diseases in hematologic response with indications for allogeneic transplantation with matched related or matched unrelated donor.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Non-Hodgkin Lymphoma
Chronic Myeloid Leukemia
Myelodysplastic Syndrome
Prior therapy
Cannot have received: allogeneic transplantation of hematopoietic cells
Repeated allogeneic transplantation of hematopoietic cells
Lab requirements
Kidney function
creatinine more than 2 norms [excluded]; Creatinine clearance below 60ml/min/1.73m2 [excluded]
Liver function
ALT, AST more than 5 norms; bilirubin more than 1.5 normal [excluded]
Cardiac function
Severe cardiac pathology, including a decrease in ejection fraction <50%, unstable angina, exertional angina of III-IV functional class, heart failure of III-IV functional class, arrhythmia grade V according to Lawn [excluded]
Severe organ failure: creatinine more than 2 norms; ALT, AST more than 5 norms; bilirubin more than 1.5 normal; Creatinine clearance below 60ml/min/1.73m2; Severe cardiac pathology, including a decrease in ejection fraction <50%, unstable angina, exertional angina of III-IV functional class, heart failure of III-IV functional class, arrhythmia grade V according to Lawn
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT06508099 currently recruiting?
Yes, this trial is currently recruiting patients.
Are there prior therapy exclusions?
Yes. Prior allogeneic transplantation of hematopoietic cells disqualifies patients from enrollment.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualify