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OncoMatch/Clinical Trials/NCT06503263

Zanubrutinib and Lenalidomide as Maintenance Therapy in DLBCL

Is NCT06503263 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Zanubrutinib plus Lenalidomide as Maintenance Therapy for diffuse large b-cell lymphoma.

Phase 2RecruitingNavy General Hospital, BeijingNCT06503263Data as of Jun 2026Location: China

Treatment: Zanubrutinib plus Lenalidomide as Maintenance TherapyThe goal of this phase 2 trial is to test the safety and efficacy of zanubrutinib and lenalidomide as maintenance therapy in patients with DLBCL.

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Extracted eligibility criteria

Treatments studied

Other

Zanubrutinib plus Lenalidomide as Maintenance Therapy

Cancer type

Diffuse Large B-Cell Lymphoma

Non-Hodgkin Lymphoma

Demographics

Ages ≥ 14

Prior therapy

Must have received: chemotherapy — induction

Patient has recieved complete remission and has completed planed courses of chemotherapy

Lab requirements

Blood counts

ANC ≥ 1.5 x 10^9/L (≥ 1 x 10^9/L if bone marrow involvement by lymphoma); Platelet ≥ 75 x 10^9/L (≥ 50 x 10^9/L if BM involvement by lymphoma); Hemoglobin ≥ 8 g/dL

Meet the following lab criteria: Absolute Neutrophil Count (ANC) ≥ 1,5 x 10^9/L (≥ 1 x 10^9/L if bone marrow (BM) involvement by lymphoma);Platelet ≥ 75 x 10^9/L (≥ 50 x 10^9/L if BM involvement by lymphoma); Hemoglobin ≥ 8 g/dL.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06503263 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received chemotherapy.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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