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OncoMatch/Clinical Trials/NCT06503211

On the Safety, Tolerability, and Efficacy of UTAA09 Injection in the Treatment of Lymphoma

Is NCT06503211 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies UTAA09 for recurrent or refractory b-cell non hodgkin's lymphoma.

Phase 1RecruitingThe First Affiliated Hospital with Nanjing Medical UniversityNCT06503211Data as of May 2026

Treatment: UTAA09The main research objective is to evaluate the safety, tolerability, and pharmacokinetic characteristics of UTAA09 cell preparation in the treatment of relapsed/refractory B-cell non Hodgkin's lymphoma patients. The secondary research objective is to explore the clinical efficacy of UTAA09 injection after administration and to explore the content of CD19 positive B cells in peripheral blood after UTAA09 injection administration.

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Extracted eligibility criteria

Cancer type

Hodgkin Lymphoma

Biomarker criteria

Required: CD19 positivity

Required: CD20 positivity

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: chimeric antigen receptor therapy

Received other chimeric antigen receptor therapy or gene modified cell therapy before screening

Cannot have received: gene modified cell therapy

Received other chimeric antigen receptor therapy or gene modified cell therapy before screening

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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