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OncoMatch/Clinical Trials/NCT06494371

A Study of LCAR-HL30 in Subjects With Relapsed/Refractory Hodgkin's Lymphoma and Anaplastic Large Cell Lymphoma

Is NCT06494371 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies LCAR-HL30 cells for hodgkin's lymphoma.

Phase 1RecruitingRuijin HospitalNCT06494371Data as of Jun 2026Location: China

Treatment: LCAR-HL30 cellsThis is a prospective, single-arm, open-label, exploratory clinical study of LCAR-HL30 in adult subjects with relapsed/refractory Hodgkin's Lymphoma and Anaplastic Large Cell Lymphoma.

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Extracted eligibility criteria

Treatments studied

Other

LCAR-HL30 cells

Cancer type

Hodgkin Lymphoma

Non-Hodgkin Lymphoma

Biomarker criteria

Required: CD30 positive expression

positive CD30 expression

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Demographics

Ages ≤ 75

Prior therapy

Cannot have received: car-t cell therapy

Cannot have received: allogeneic hematopoietic stem cell transplantation

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06494371 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior car-t cell therapy, allogeneic hematopoietic stem cell transplantation disqualifies patients from enrollment.

Does this trial require CD30?

Yes, CD30 positive expression is a required biomarker for enrollment.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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