OncoMatch

OncoMatch/Clinical Trials/NCT06481592

A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

Is NCT06481592 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Lifileucel for endometrial cancer.

Phase 2RecruitingIovance Biotherapeutics, Inc.NCT06481592Data as of Jun 2026

Treatment: LifileucelThe purpose of this study is to investigate the efficacy and safety of the lifileucel regimen in participants with previously treated endometrial cancer.

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Extracted eligibility criteria

Treatments studied

Other

Lifileucel

Cancer type

Endometrial Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 70
Female only

Prior therapy

Max 4 prior lines
Min 1 prior line

Must have received: platinum-based chemotherapy

Must have received: anti-pd-1/pd-l1 therapy

Lab requirements

Cardiac function

adequate cardiopulmonary function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Honor Health · Phoenix, Arizona
  • University of Southern California · Los Angeles, California
  • Orlando Health · Orlando, Florida
  • H. Lee Moffitt Cancer Center and Research Institute, Inc. · Tampa, Florida
  • Augusta University · Augusta, Georgia

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT06481592 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received platinum-based chemotherapy and anti-pd-1/pd-l1 therapy.

Is there an age limit?

Yes. Patients must be 70 years or younger.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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