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OncoMatch/Clinical Trials/NCT06478108

Interventional Software for Multi-immunotherapy of Solid Tumors

Is NCT06478108 recruiting? Yes, currently enrolling (May 2026). This Phase 2/3 trial studies IRSW-MIM for lung cancer.

Phase 2/3RecruitingSecond Affiliated Hospital of Guangzhou Medical UniversityNCT06478108Data as of May 2026

Treatment: IRSW-MIMThis trial is designed to investigate the safety, response rates and survival outcomes of patients with advanced solid tumors by intra-tumor (IT) injection of multiple drugs including CTLA4, PD1, and/or PDL1 antibodies combined with drugs-eluting beads loaded with IL2, chemodrug, anti-angiogenesis drug, et. al that will be recommended by an AI-based medical software named IRSW-MIM developed by a cooperating company.

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Hepatocellular Carcinoma

Tumor Agnostic

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: clinical trial participation

Patients participated in clinical trials of equipment or drugs (signed informed consent) within 4 weeks

Lab requirements

Blood counts

WBC ≥ 3.0×10E9/L; Hb ≥ 90g/L; PLT ≥ 50×10E9/L; INR < 2.3 or PT < 6 seconds above control

Kidney function

Cr ≤ 145.5 umul/L

Liver function

Child-Pugh class A or B/Child score > 7; Albumin > 28 g/L; Total bilirubin < 51 μmol/L

Child-Pugh class A or B/Child score > 7; WBC≥3.0×10E9/L; Hb≥90g/L; PLT ≥50×10E9/L;INR < 2.3 or PT < 6 seconds above control;Cr ≤ 145.5 umul/L;Albumin > 28 g/L;Total bilirubin < 51 μmol/L

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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