OncoMatch/Clinical Trials/NCT06477692
Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy
Is NCT06477692 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies ENI using IMRT with or without chemotherapy for head and neck cancer.
Treatment: ENI using IMRT with or without chemotherapy — To determine the risk of solitary elective volume recurrence following involved nodal radiotherapy (INRT) versus elective nodal irradiation (ENI)
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Head and Neck Squamous Cell Carcinoma
Disease stage
Required: Stage I, II, III, IVA, IVB (AJCC 7th edition)
Excluded: Stage I GLOTTIC CANCER, II GLOTTIC CANCER
Clinical stage I-IVB (AJCC, 7th edition); stages I-II glottic cancer are excluded
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Demographics
Prior therapy
Cannot have received: systemic chemotherapy
Exception: prior chemotherapy for a remote cancer is allowable
Prior systemic chemotherapy for the study cancer; prior chemotherapy for a remote cancer is allowable.
Cannot have received: radiation therapy
Exception: if would result in overlap of radiation fields
Prior radiotherapy to the region of the study cancer that would result in overlap of radiation fields.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- UT Southwestern Medical Center · Dallas, Texas
Showing up to 5 US sites.
See all sites on ClinicalTrials.gov →Frequently asked questions
Is NCT06477692 currently recruiting?
Yes, this trial is currently recruiting patients.
Are there prior therapy exclusions?
Yes. Prior systemic chemotherapy, radiation therapy disqualifies patients from enrollment.
What disease stage is eligible?
Stage I or II or III or IVA or IVB is required.
Is there an age limit?
Yes. Patients must be 99 years or younger.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages