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OncoMatch/Clinical Trials/NCT06472739

The Effect of GM-CSF to Preventing Oral Mucositis for Patients With Nasopharyngeal Carcinoma Receiving Radiotherapy

Is NCT06472739 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies GM-CSF for gm-csf.

Phase 2RecruitingSun Yat-sen UniversityNCT06472739Data as of Jun 2026Location: China

Treatment: GM-CSFTo evaluate the efficacy of GM-CSF to preventing oral mucositis for patients with nasopharyngeal carcinoma receiving radiotherapy.

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Extracted eligibility criteria

Treatments studied

Other

GM-CSF

Disease stage

Required: Stage II, III, IVA

Excluded: Stage I, IVB

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 65

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: radiotherapy

Exception: except for non-melanomatous skin cancers outside intended RT treatment volume

History of previous radiotherapy (except for non-melanomatous skin cancers outside intended RT treatment volume)

Cannot have received: chemotherapy

Prior chemotherapy or surgery (except diagnostic) to primary tumor or nodes

Cannot have received: surgery

Exception: except diagnostic

Prior chemotherapy or surgery (except diagnostic) to primary tumor or nodes

Lab requirements

Blood counts

wbc≥4×109/l, plt≥100×109/l, hgb≥90g/l

Kidney function

creatinine clearance rate≥60 ml/min or creatinine< 1.5×uln

Liver function

alt, ast <1.5×uln concomitant with alp ≤2.5×uln, and bilirubin ≤uln

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06472739 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

What disease stage is eligible?

Stage II or III or IVA is required.

Is there an age limit?

Yes. Patients must be 65 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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