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OncoMatch/Clinical Trials/NCT06471205

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Unresectable Locally Advanced or Recurrent Metastatic Triple-negative Breast Cancer

Is NCT06471205 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including BL-B01D1 and PD-1 Monoclonal Antibody for triple-negative breast cancer.

Phase 2RecruitingSichuan Baili Pharmaceutical Co., Ltd.NCT06471205Data as of May 2026

Treatment: BL-B01D1 · PD-1 Monoclonal AntibodyThis phase II study is a clinical study to explore the efficacy and safety of BL-B01D1 combined with PD-1 monoclonal antibody in patients with unresectable locally advanced or recurrent metastatic triple-negative breast cancer.

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Extracted eligibility criteria

Cancer type

Triple-Negative Breast Cancer

Breast Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: antibody-drug conjugate with topoisomerase I inhibitor payload

ADC drugs that have received topoisomerase I inhibitors as small molecule toxins

Cannot have received: checkpoint inhibitor

Exception: prior to neoadjuvant/adjuvant chemotherapy

Patients with checkpoint inhibitors prior to neoadjuvant/adjuvant chemotherapy

Cannot have received: immunomodulatory drug

Use of an immunomodulatory drug within 14 days before the first dose of study drug

Cannot have received: palliative radiotherapy

Palliative radiotherapy within 2 weeks before the first dose

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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