OncoMatch

OncoMatch/Clinical Trials/NCT06455917

TIL Therapy in Non-small-cell Lung Cancer (NSCLC) Patients

Is NCT06455917 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies TILs(Tumor Infiltrating Lymphocytes) for non-small cell lung cancer.

Phase 2RecruitingUniversity Hospital, Basel, SwitzerlandNCT06455917Data as of May 2026

Treatment: TILs(Tumor Infiltrating Lymphocytes)Aim of the study is to investigate the efficacy and safety of adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TIL) in patients with advanced pre-treated non-small cell lung cancer (NSCLC).

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 1 prior line

Must have received: standard therapy

Disease progression after at least one standard therapy and without any approved curative-intended treatment option.

Lab requirements

Blood counts

adequate hematological function per investigator's judgment

Kidney function

adequate renal function per investigator's judgment

Liver function

adequate hepatic function per investigator's judgment

Cardiac function

adequate cardiovascular function per investigator's judgment; cardiac stress testing required for all patients with underlying cardiac conditions and patients with age ≥ 50 years

Adequate organ function (pulmonary, cardiovascular, hematological, hepatic, and renal function) per investigator's judgment. Cardiac stress testing is required for all patients with underlying cardiac conditions and patients with age ≥ 50 years.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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