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OncoMatch/Clinical Trials/NCT06455358

61Cu-NODAGA-LM3 PET/CT for the Detection of Neuroendocrine Tumors (COPPER PET in NET)

Is NCT06455358 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies 61Cu-NODAGA-LM3 for neuroendocrine tumors.

Phase 1/2RecruitingUniversity Hospital, Basel, SwitzerlandNCT06455358Data as of May 2026

Treatment: 61Cu-NODAGA-LM3The goal of this monocentric, open-label, randomized-controlled, reader-blind clinical study is to assess the safety of the radiolabeled somatostatin receptor ligand, 61Cu-NODAGA-LM3, and its sensitivity in comparison to the standard of care, 68Ga-DOTATOC, for PET/CT imaging in patients with well differentiated bronchopulmonary and gastroenteropancreatic neuroendocrine tumors.

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Extracted eligibility criteria

Cancer type

Neuroendocrine Tumor

Prior therapy

Cannot have received: radiopharmaceutical

Prior or planned administration of a radiopharmaceutical within 8 half-lives of the radionuclide used on such radiopharmaceutical including at any time during the current study

Cannot have received: active anti-tumor treatment

Exception: continuation of long acting somatostatin analogues

Initiation or continuation of active anti-tumor treatment between 61Cu-NODAGA-LM3 and 68Ga-DOTATOC PET/CT, except continuation of long acting somatostatin analogues

Lab requirements

Kidney function

estimated egfr (ckd-epi) ≥ 45 ml/min

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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