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OncoMatch/Clinical Trials/NCT06451861

Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AML

Is NCT06451861 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments for acute myeloid leukemia.

Phase 2RecruitingGuangdong Provincial People's HospitalNCT06451861Data as of Jun 2026Location: China

Treatment: Chidamide · Venetoclax · azacitidine · Anthracyclines or anthraquinones · cytarabineTo compare the efficacy and safty of ABC-14 regimen with the traditional "3+7" regimen or AB-14 regimen in the treatment of newly diagnosed acute myeloid leukaemia

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Extracted eligibility criteria

Treatments studied

Targeted therapy

ChidamideVenetoclax

Chemotherapy

azacitidinecytarabine

Other

Anthracyclines or anthraquinones

Cancer type

Acute Myeloid Leukemia

Performance status

ECOG 0–4(Completely disabled)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06451861 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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