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OncoMatch/Clinical Trials/NCT06447597

A Clinical Study of B007 in the Treatment of Generalized Myasthenia Gravis.

Is NCT06447597 recruiting? Yes, currently enrolling (May 2026). This Phase 2/3 trial studies B007 for generalized myasthenia gravis.

Phase 2/3RecruitingShanghai Jiaolian Drug Research and Development Co., LtdNCT06447597Data as of May 2026

Treatment: B007The purpose of this study is to evaluate the efficacy and safety of B007 in subjects with generalized myasthenia gravis.

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Extracted eligibility criteria

Biomarker criteria

Required: CHRNA1 antibody positive

Serum AchR(Acetylcholine receptor)-Ab ... was positive during screening

Required: MUSK antibody positive

Serum ... MUSK-Ab was positive during screening

Disease stage

Excluded: Stage MGFA I, MGFA V

Subjects with MGFA I and V type [excluded]

Prior therapy

Min 1 prior line

Must have received: standard of care for generalized myasthenia gravis

subjects received at least one gMG stable dose of SoC, and maintain a stable dose throughout the test

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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