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OncoMatch/Clinical Trials/NCT06427460

Central-boost Ablative Radiation Therapy for Solid Tumors (CBART)

Is NCT06427460 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for pancreatic cancer.

Phase 2RecruitingChanghai HospitalNCT06427460Data as of May 2026

In the case of large tumors or tumors closely adjacent to organs at risk, ablative doses offered by stereotactic body radiation therapy (SBRT) could not be delivered. Therefore, a technique that could provide high radiation doses to tumors without increasing of risks of severe adverse effects is required.

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Extracted eligibility criteria

Cancer type

Pancreatic Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: radiation therapy

Lab requirements

Blood counts

White blood cell count ≥4.0×10^9/L, neutrophil count ≥2.0×10^9, hemoglobin level ≥100g/L, platelet count ≥100×10^9/L

Kidney function

creatinine level within the normal

Liver function

ALT and AST level < 2.5 times the upper limit of normal, total bilirubin level within the normal

No abnormality in blood routine test, liver and kidney function test and coagulation test (White blood cell count ≥4.0×10^9/L, neutrophil count ≥2.0×10^9, hemoglobin level ≥100g/L, platelet count ≥100×10^9/L, ALT and AST level < 2.5 times the upper limit of normal, total bilirubin and creatinine level within the normal, international normalized ratio <2)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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