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OncoMatch/Clinical Trials/NCT06402708

Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)

Is NCT06402708 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies Chemotherapy for thymic carcinoma.

Phase 3RecruitingFudan UniversityNCT06402708Data as of Jun 2026Location: China

Treatment: ChemotherapyThe goal of this clinical trial is to learn the role of adjuvant chemotherapy for patients with thymic carcinoma and completed resection. The main questions it aims to answer are: 1. Does adjuvant chemotherapy decrease disease progression? 2. Does medium dose of three drugs (paclitaxel, cisplatin, 5-FU) well tolerance? Researchers will compare chemoradiotherapy to radiotherapy to see whether chemoradiotherapy could decrease disease progression or not. Participants will: 1. Take radiotherapy (50Gy/25f) with or without 4 cycles of chemotherapy (TPF). 2. Follow up every 3 months in the first two year, and then every 6 months.

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Extracted eligibility criteria

Treatments studied

Other

Chemotherapy

Disease stage

Required: Stage I, II, III

Demographics

Ages ≤ 75

Lab requirements

Blood counts

White blood cells ≥ 3 × 10^9/L; Neutrophils ≥ 1.5 × 10^9/L; Hemoglobin ≥ 10 g/dL; Platelets ≥ 100 × 10^9/L

Kidney function

Creatinine ≤ 1.5 times the upper limit of normal value

Liver function

Total bilirubin ≤ 1.5 times the upper limit of normal value; AST (SGOT)/ALT (SGPT) ≤ 2.5 times the upper limit of normal value

Cardiac function

No severe heart dysfunction; Symptomatic coronary heart disease and left heart failure excluded

No severe hematopoietic function, heart, lung, liver, kidney dysfunction, or immune deficiency; White blood cells ≥ 3 × 10^9/L; Neutrophils ≥ 1.5 × 10^9/L; Hemoglobin ≥ 10 g/dL; Platelets ≥ 100 × 10^9/L; Total bilirubin ≤ 1.5 times the upper limit of normal value; AST (SGOT)/ALT (SGPT) ≤ 2.5 times the upper limit of normal value; Creatinine ≤ 1.5 times the upper limit of normal value

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06402708 currently recruiting?

Yes, this trial is currently recruiting patients.

What disease stage is eligible?

Stage I or II or III is required.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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