OncoMatch/Clinical Trials/NCT06397235
DEB-TACE+RALOX-HAIC vs DEB-TACE for Large HCC
Is NCT06397235 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including DEB-TACE+HAIC and DEB-TACE for hepatocellular carcinoma non-resectable.
Treatment: DEB-TACE+HAIC · DEB-TACE — This study is conducted to evaluate the efficacy and safety of transarterial chemoembolization with drug-eluting beads (DEB-TACE) combined with hepatic artery infusion chemotherapy (HAIC) with oxaliplatin and raltitrexed (RALOX-HAIC) versus DEB-TACE alone for unresectable large hepatocellular carcinoma (HCC).
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Hepatocellular Carcinoma
Performance status
ECOG 0–1(Restricted strenuous activity)
Demographics
Prior therapy
Cannot have received: palliative treatment (TACE, transcatheter arterial embolization, HAIC, radiation therapy, systemic therapy)
Previous palliative treatments, including TACE, transcatheter arterial embolization, HAIC, radiation therapy, systemic therapy
Lab requirements
Blood counts
platelet count ≥75×10^9/L, leukocyte >3.0×10^9/L, Neutrophil count ≥1.5×10^9/L
Kidney function
creatinine clearance≤1.5×ULN
Liver function
Child-Pugh score 5-7; ASL and AST≤5×ULN; prolongation of prothrombin time ≤4 seconds
Adequate organ and hematologic function with platelet count ≥75×10^9/L, leukocyte >3.0×10^9/L, Neutrophil count ≥1.5×10^9/L, ASL and AST≤5×ULN, creatinine clearance≤1.5×ULN, and prolongation of prothrombin time ≤4 seconds
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT06397235 currently recruiting?
Yes, this trial is currently recruiting patients.
Are there prior therapy exclusions?
Yes. Prior palliative treatment disqualifies patients from enrollment.
Is there an age limit?
Yes. Patients must be 75 years or younger.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages