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OncoMatch/Clinical Trials/NCT06391034

Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer

Is NCT06391034 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Non-interventional hormone therapy and hyperpolarized pyruvate +/-urea (13C/15N) for prostate cancer.

Phase 2RecruitingRobert Bok, MD, PhDNCT06391034Data as of Jun 2026

Treatment: hyperpolarized pyruvate +/-urea (13C/15N) · Non-interventional hormone therapyThis is a Phase 2 clinical study of hyperpolarized (HP) 13C-pyruvate (13C), 15N-urea (13C,15N) metabolic MR imaging in prostate cancer patients who are undergoing or have received radiation therapy for prostate cancer.

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Extracted eligibility criteria

Treatments studied

Other

hyperpolarized pyruvate +/-urea (13C/15N)Non-interventional hormone therapy

Cancer type

Prostate Cancer

Disease stage

Excluded: Stage PELVIC REGIONAL OR DISTANT METASTATIC DISEASE

Evidence of pelvic regional or distant metastatic disease on conventional imaging (MRI, computed tomography or whole body bone scan) or prostate-specific membrane antigen (PSMA) Positron Emission Tomography (PET) imaging. PSMA-avid lymph nodes confined to the pelvis will be allowed if <1 centimeter (cm).

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Male only

Lab requirements

Blood counts

White Blood Cell count (WBC) >=4000 cells/μL; Hemoglobin ≥9.0 gm/dL; Platelets ≥75,000 cells/μL

Kidney function

Renal Function > 30 Epithelial Growth Factor Receptor (eGFR)

Demonstrates adequate organ function as defined below: White Blood Cell count (WBC) >=4000 cells/μL. Hemoglobin ≥9.0 gm/dL. Platelets ≥75,000 cells/μL. Renal Function > 30 Epithelial Growth Factor Receptor (eGFR).

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of California, San Francisco · San Francisco, California

Showing up to 5 US sites.

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Frequently asked questions

Is NCT06391034 currently recruiting?

Yes, this trial is currently recruiting patients.

Is this trial open to female patients?

No. This trial enrolls male patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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