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OncoMatch/Clinical Trials/NCT06383520

Study on the Clinical Application Value of PET Imaging Targeting GPC3 in Hepatocellular Carcinoma

Is NCT06383520 recruiting? Yes, currently enrolling (Sep 2026). This Early Phase 1 trial studies 68Ga-aGPC3-scFv/Fab for malignant neoplasm of liver.

Early Phase 1RecruitingUnion Hospital, Tongji Medical College, Huazhong University of Science and TechnologyNCT06383520Data as of Sep 2026Location: China

Treatment: 68Ga-aGPC3-scFv/FabThis is a diagnostic study. Patients were recruited from patients with clinically suspected or confirmed hepatocellular carcinoma and healthy volunteers were recruited for PET/or PET/CT imaging targeting a GPC3-specific probe (in the case of 68Ga-NOTA-aGPC3-scFv) , to observe the reaction of volunteers and patients after injection of drugs, to evaluate the pharmacokinetics in vivo and the efficacy of diagnosis and staging, and to perform PET CT imaging in patients with contraindications. General Information, clinical data, blood routine, liver and renal function, and other imaging data were collected. The final diagnosis was based on the histopathology of biopsy or surgical specimens.

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Extracted eligibility criteria

Treatments studied

Other

68Ga-aGPC3-scFv/Fab

Cancer type

Hepatocellular Carcinoma

Demographics

Ages ≤ 65

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06383520 currently recruiting?

Yes, this trial is currently recruiting patients.

Is there an age limit?

Yes. Patients must be 65 years or younger.

Could you qualify for this trial?

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