OncoMatch/Clinical Trials/NCT06383520
Study on the Clinical Application Value of PET Imaging Targeting GPC3 in Hepatocellular Carcinoma
Is NCT06383520 recruiting? Yes, currently enrolling (May 2026). This Early Phase 1 trial studies 68Ga-aGPC3-scFv/Fab for malignant neoplasm of liver.
Treatment: 68Ga-aGPC3-scFv/Fab — This is a diagnostic study. Patients were recruited from patients with clinically suspected or confirmed hepatocellular carcinoma and healthy volunteers were recruited for PET/or PET/CT imaging targeting a GPC3-specific probe (in the case of 68Ga-NOTA-aGPC3-scFv) , to observe the reaction of volunteers and patients after injection of drugs, to evaluate the pharmacokinetics in vivo and the efficacy of diagnosis and staging, and to perform PET CT imaging in patients with contraindications. General Information, clinical data, blood routine, liver and renal function, and other imaging data were collected. The final diagnosis was based on the histopathology of biopsy or surgical specimens.
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For patients with hepatocellular carcinoma.
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