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OncoMatch/Clinical Trials/NCT06378346

GU-01: Glycyrrhizin in Prostate Cancer

Is NCT06378346 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Glycyrrhizin - 75 mg and Glycyrrhizin - 150 mg for prostate cancer.

Phase 2RecruitingUniversity of Illinois at ChicagoNCT06378346Data as of Jun 2026

Treatment: Glycyrrhizin - 75 mg · Glycyrrhizin - 150 mgThis is a pilot, randomized, window-of-opportunity treatment trial in which participants with previously untreated prostate cancer (PCa) who are candidates for surgery (radical prostatectomy)

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Extracted eligibility criteria

Treatments studied

Other

Glycyrrhizin - 75 mgGlycyrrhizin - 150 mg

Cancer type

Prostate Cancer

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Demographics

Male only

Prior therapy

Cannot have received: chemotherapy

Exception: within 30 days of starting study treatment

Previous chemotherapy, biological therapy, radiation therapy, androgens, thalidomide, immunotherapy, other anticancer agents and/or investigational agents within 30 days of starting study treatment.

Cannot have received: biological therapy

Exception: within 30 days of starting study treatment

Previous chemotherapy, biological therapy, radiation therapy, androgens, thalidomide, immunotherapy, other anticancer agents and/or investigational agents within 30 days of starting study treatment.

Cannot have received: radiation therapy

Exception: within 30 days of starting study treatment

Previous chemotherapy, biological therapy, radiation therapy, androgens, thalidomide, immunotherapy, other anticancer agents and/or investigational agents within 30 days of starting study treatment.

Cannot have received: androgen

Exception: within 30 days of starting study treatment

Previous chemotherapy, biological therapy, radiation therapy, androgens, thalidomide, immunotherapy, other anticancer agents and/or investigational agents within 30 days of starting study treatment.

Cannot have received: immunotherapy

Exception: within 30 days of starting study treatment

Previous chemotherapy, biological therapy, radiation therapy, androgens, thalidomide, immunotherapy, other anticancer agents and/or investigational agents within 30 days of starting study treatment.

Cannot have received: other anticancer agents (thalidomide)

Exception: within 30 days of starting study treatment

Previous chemotherapy, biological therapy, radiation therapy, androgens, thalidomide, immunotherapy, other anticancer agents and/or investigational agents within 30 days of starting study treatment.

Cannot have received: investigational agent

Exception: within 30 days of starting study treatment

Previous chemotherapy, biological therapy, radiation therapy, androgens, thalidomide, immunotherapy, other anticancer agents and/or investigational agents within 30 days of starting study treatment.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Illinois · Chicago, Illinois

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT06378346 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior chemotherapy, biological therapy, radiation therapy disqualifies patients from enrollment.

Is this trial open to female patients?

No. This trial enrolls male patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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