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OncoMatch/Clinical Trials/NCT06371157

A Study of AK104+Lenvatinib in Combination With Transarterial Chemoembolization (TACE) Versus TACE in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma

Is NCT06371157 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies multiple treatments including AK104 and Lenvatinib for hepatocellular carcinoma.

Phase 3RecruitingAkesoNCT06371157Data as of Jun 2026Location: China

Treatment: AK104 · LenvatinibA study to evaluate cadonilimab (AK104) + lenvatinib in combination with transarterial chemoembolization (TACE) versus TACE in participants with incurable/non-metastatic hepatocellular carcinoma

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Extracted eligibility criteria

Treatments studied

Targeted therapy

Lenvatinib

Other

AK104

Cancer type

Hepatocellular Carcinoma

Disease stage

Excluded: Stage IV

No evidence of metastasis; Not amenable to curative surgery or transplantation or curative ablation but amenable to TACE

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75

Lab requirements

Liver function

child pugh score class a

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06371157 currently recruiting?

Yes, this trial is currently recruiting patients.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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