OncoMatch/Clinical Trials/NCT06352008
To Evaluate the Efficacy and Safety of Anlotinib Hydrochloride Capsule in Postoperative Non-pCR Patients With Non-small Cell Lung Cancer
Is NCT06352008 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Anlotinib for non-small cell lung cancer.
Treatment: Anlotinib — To explore the effectiveness of anlotinib hydrochloride capsule in postoperative non-pCR non-small cell lung cancer patients with adjuvant intensive therapy
Check if I qualifyExtracted eligibility criteria
Cancer type
Non-Small Cell Lung Carcinoma
Biomarker criteria
Required: EGFR wild-type
Subjects are known to have genetic abnormalities that have been approved for targeted drug therapy (non-squamous cell carcinoma subjects are required to have EGFR or ALK gene tested or provide previous test reports during the screening period)
Required: ALK wild-type
Subjects are known to have genetic abnormalities that have been approved for targeted drug therapy (non-squamous cell carcinoma subjects are required to have EGFR or ALK gene tested or provide previous test reports during the screening period)
Disease stage
Required: Stage IIA, IIB, IIIA (AJCC/UICC 8th edition)
Patients with stage IIA-IIIA NSCLC ... AJCC/UICC 8th edition
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Must have received: anti-PD-1 therapy — neoadjuvant
previously received PD-1/PD-L1 inhibitors combined with chemotherapy neoadjuvant therapy
Must have received: anti-PD-L1 therapy — neoadjuvant
previously received PD-1/PD-L1 inhibitors combined with chemotherapy neoadjuvant therapy
Must have received: chemotherapy — neoadjuvant
previously received PD-1/PD-L1 inhibitors combined with chemotherapy neoadjuvant therapy
Must have received: surgery — definitive (R0 resection)
underwent R0 resection for curative purposes before surgery
Cannot have received: Chinese patent medicines with anti-tumor indications (compound Cantharides capsule, Kangai injection, Kanglaite capsule/injection, Aidi injection, Bruceae oil injection/capsule, Xiaoaipingtablet/injection, hualbufatin capsule)
Within 2 weeks before starting the administration, it has been treated with Chinese patent medicines (including compound Cantharides capsule, Kangai injection, Kanglaite capsule/injection, Aidi injection, Bruceae oil injection/capsule, Xiaoaipingtablet/injection, hualbufatin capsule, etc.) with anti-tumor indications specified in the NMPA approved drug instructions
Lab requirements
Blood counts
Kidney function
Liver function
The main organs function well and meet the standards
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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