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OncoMatch/Clinical Trials/NCT06349889

Adebrelimab and Chemoradiotherapy in High-risk LANPC

Is NCT06349889 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Adebrelimab for nasopharyngeal carcinoma.

Phase 2RecruitingSun Yat-sen UniversityNCT06349889Data as of Jun 2026Location: China

Treatment: AdebrelimabThis trial aims to study the role of Adebrelimab combined with induction chemotherapy plus concurrent chemoradiotherapy (IC+CCRT) for high-risk locoregionally advanced nasopharyngeal carcinoma(LANPC).

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Adebrelimab

Cancer type

Head and Neck Squamous Cell Carcinoma

Disease stage

Required: Stage IVA+T3N2M0

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 65

Lab requirements

Blood counts

neutrocyte count ≥1.5×10e9/L, hemoglobin ≥90g/L, platelet count ≥100×10e9/L

Kidney function

creatinine clearance rate ≥ 60 ml/min (Cockcroft-Gault formula)

Liver function

ALT/AST ≤2.5×ULN, bilirubin ≤1.5×ULN

Adequate marrow function: neutrocyte count≥1.5×10e9/L, hemoglobin ≥90g/L and platelet count ≥100×10e9/L. ALT/AST ≤2.5×ULN, bilirubin ≤1.5×ULN. Adequate renal function: creatinine clearance rate ≥ 60 ml/min (Cockcroft-Gault formula).

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06349889 currently recruiting?

Yes, this trial is currently recruiting patients.

What disease stage is eligible?

Stage IVA+T3N2M0 is required.

Is there an age limit?

Yes. Patients must be 65 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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