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OncoMatch/Clinical Trials/NCT06333262

Fixed Duration Pirtobrutinib and Obinutuzumab in Chronic Lymphocytic Leukemia

Is NCT06333262 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Pirtobrutinib and Obinutuzumab for chronic lymphocytic leukemia.

Phase 2RecruitingInhye AhnNCT06333262Data as of May 2026

Treatment: Pirtobrutinib · ObinutuzumabThis study will evaluate fixed-duration therapy with pirtobrutinib and obinutuzumab given over 12 cycles (approximately 1 year) as first-line treatment of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL or SLL).

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Extracted eligibility criteria

Cancer type

Chronic Lymphocytic Leukemia

Non-Hodgkin Lymphoma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Lab requirements

Blood counts

Adequate organ and bone marrow function as defined by the study protocol

Kidney function

Adequate organ and bone marrow function as defined by the study protocol

Liver function

Adequate organ and bone marrow function as defined by the study protocol

Adequate organ and bone marrow function as defined by the study protocol

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • New England Cancer Specialists · Scarborough, Maine
  • Beth Israel Deaconess Medical Center · Boston, Massachusetts
  • Brigham & Women's Hospital · Boston, Massachusetts
  • Dana-Farber Cancer Institute · Boston, Massachusetts

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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