OncoMatch/Clinical Trials/NCT06327139

Optimising Patient Experience in Head and Neck Radiotherapy

Is NCT06327139 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including Conventional 5 point closed face immobilisation mask. and 5 point open face immobilization mask for head and neck cancer.

Treatment: Conventional 5 point closed face immobilisation mask. · 5 point open face immobilization mask · 3 point open face immobilization mask — This study is a phase III, randomized, single-centre, multiple arm trial examining the set-up accuracy of three different types of immobilization methods for head and neck cancer patients receiving radical radiation therapy. The methods of immobilization under investigation in this study are two types of open faced head and neck masks compared with the convention closed faced head and neck mask. Patients receiving treatment using an open faced mask will have their intra fraction motion monitored through the use of intra fraction surface guided monitoring. The study aims to determine the set-up accuracy of the three types of immobilization through measuring the magnitude of the translational corrections on the daily cone beam computed tomography (CBCT). To be eligible for the study a patient must be planned to receive a minimum of 30 fractions of head and neck radiation therapy. Patients distress levels associated with each type of immobilization device will be measured using the psychological measure General Health Questionnaire-12 (GHQ-12) which will be collected at the beginning and end of their course of radiation therapy treatment.