OncoMatch

OncoMatch/Clinical Trials/NCT06326736

Study of Neoantigen mRNA Vaccines in Patients With Resectable Pancreatic Cancer

Is NCT06326736 recruiting? Yes, currently enrolling (Jun 2026). This Early Phase 1 trial studies multiple treatments including SJ-Neo006 and Camrelizumab for pancreatic cancer.

Early Phase 1RecruitingJinling Hospital, ChinaNCT06326736Data as of Jun 2026Location: China

Treatment: Camrelizumab · SJ-Neo006 · Gemcitabine+AbraxaneThe purpose of this study is to evaluate the safety and efficacy of treating pancreatic cancer with surgery to remove cancerour tissue, followed by camrelizumab and a personalized cancer mRNA vaccines.

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Camrelizumab

Chemotherapy

Gemcitabine+Abraxane

Other

SJ-Neo006

Cancer type

Pancreatic Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: chemotherapy

Subjects must not have had prior chemotherapy, radiation therapy, or immunotherapy for Pancreatic ductal adenocarcinoma(PDAC)

Cannot have received: radiation therapy

Subjects must not have had prior chemotherapy, radiation therapy, or immunotherapy for Pancreatic ductal adenocarcinoma(PDAC)

Cannot have received: immunotherapy

Subjects must not have had prior chemotherapy, radiation therapy, or immunotherapy for Pancreatic ductal adenocarcinoma(PDAC)

Cannot have received: anti-PD-1 therapy

Prior neoadjuvant treatment, radiation therapy, anti-PD-1 antibody or any other immune therapy for pancreatic ductal adenocarcinoma

Lab requirements

Cardiac function

nyha class iii-iv heart failure, uncontrolled hypertension, clinically significant cardiac dysthythmia, or electrocardiogram abnormality, cerebrovascular accident, transient ischemic attack, or seizure disorder [excluded]

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06326736 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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