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OncoMatch/Clinical Trials/NCT06326736

Study of Neoantigen mRNA Vaccines in Patients With Resectable Pancreatic Cancer

Is NCT06326736 recruiting? Yes, currently enrolling (May 2026). This Early Phase 1 trial studies multiple treatments including SJ-Neo006 and Camrelizumab for pancreatic cancer.

Early Phase 1RecruitingJinling Hospital, ChinaNCT06326736Data as of May 2026

Treatment: Camrelizumab · SJ-Neo006 · Gemcitabine+AbraxaneThe purpose of this study is to evaluate the safety and efficacy of treating pancreatic cancer with surgery to remove cancerour tissue, followed by camrelizumab and a personalized cancer mRNA vaccines.

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Extracted eligibility criteria

Cancer type

Pancreatic Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: chemotherapy

Subjects must not have had prior chemotherapy, radiation therapy, or immunotherapy for Pancreatic ductal adenocarcinoma(PDAC)

Cannot have received: radiation therapy

Subjects must not have had prior chemotherapy, radiation therapy, or immunotherapy for Pancreatic ductal adenocarcinoma(PDAC)

Cannot have received: immunotherapy

Subjects must not have had prior chemotherapy, radiation therapy, or immunotherapy for Pancreatic ductal adenocarcinoma(PDAC)

Cannot have received: anti-PD-1 therapy

Prior neoadjuvant treatment, radiation therapy, anti-PD-1 antibody or any other immune therapy for pancreatic ductal adenocarcinoma

Lab requirements

Cardiac function

nyha class iii-iv heart failure, uncontrolled hypertension, clinically significant cardiac dysthythmia, or electrocardiogram abnormality, cerebrovascular accident, transient ischemic attack, or seizure disorder [excluded]

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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