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OncoMatch/Clinical Trials/NCT06311578

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

Is NCT06311578 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies multiple treatments including JNJ-87704916 and Cetrelimab for neoplasms.

Phase 1RecruitingJohnson & Johnson Enterprise Innovation Inc.NCT06311578Data as of Jun 2026Location: International · 4 countries

Treatment: JNJ-87704916 · CetrelimabThe purpose of this study is to determine the safety, feasibility, recommended dose(s) and regimen(s) of JNJ-87704916 as monotherapy and in combination with cetrelimab.

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Extracted eligibility criteria

Treatments studied

Other

JNJ-87704916Cetrelimab

Disease stage

Required: Stage IV, III

metastatic or locally advanced NSCLC

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Must have received: all available standard of care therapy

advanced or metastatic solid tumor exhausting all available standard of care therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • NYU Langone Health · New York, New York
  • Fox Chase Cancer Center · Philadelphia, Pennsylvania
  • UPMC Cancer Centers · Pittsburgh, Pennsylvania
  • MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT06311578 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received all available standard of care therapy.

What disease stage is eligible?

Stage IV or III is required.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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