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OncoMatch/Clinical Trials/NCT06305247

A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours

Is NCT06305247 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies multiple treatments including IPN01194 and IPN01194 for melanoma.

Phase 1/2RecruitingIpsenNCT06305247Data as of May 2026

Treatment: IPN01194 · IPN01194The purpose of this study is to determine the appropriate dosage, safety and effectiveness of the study drug, IPN01194 in adults with advanced solid tumours. The participants in this study will have advanced solid tumours. 'Advanced solid tumours' refers to cancers that can occur in several places, including cancers in organs or tissues that have spread from their original site to nearby tissues or other parts of the body. In this study, all participants will receive the study drug, which will be taken by mouth (orally).

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Extracted eligibility criteria

Cancer type

Melanoma

Head and Neck Squamous Cell Carcinoma

Pancreatic Cancer

Colorectal Cancer

Tumor Agnostic

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: anti-cancer therapy

Concurrent treatment with any other anti-cancer therapy (including radiotherapy or investigational agents).

Cannot have received: investigational agent

Current enrolment or past participation in any other clinical trial involving an investigational study treatment within the last 28 days.

Lab requirements

Blood counts

Non-adequate bone marrow function [excluded]

Kidney function

Non-adequate renal function [excluded]

Liver function

Non-adequate hepatic function [excluded]

Cardiac function

Non-adequate cardiac function [excluded]

Non-adequate cardiac function; Non-adequate bone marrow function; Non-adequate renal function; Non-adequate hepatic function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • The Angeles Clinic and Research Institute - California · Los Angeles, California
  • UC San Diego Health System - La Jolla · San Diego, California
  • Yale Cancer Center - New Heaven · New Haven, Connecticut
  • Sarah Cannon Research Institute (SCRI) - Nashville · Nashville, Tennessee
  • Virginia Cancer Specialist · Fairfax, Virginia

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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