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OncoMatch/Clinical Trials/NCT06251076

Plan Development for Giving Teclistamab in the Outpatient Setting

Is NCT06251076 recruiting? Yes, currently enrolling (May 2026). This Phase 4 trial studies multiple treatments including Teclistamab and Tocilizumab for multiple myeloma.

Phase 4RecruitingUniversity Health Network, TorontoNCT06251076Data as of May 2026

Treatment: Teclistamab · TocilizumabThis is a pilot study to develop an outpatient-based process for the administration of teclistamab for for relapsed/refractory multiple myeloma patients and to evaluate the burden on caregivers of patients receiving outpatient administration of teclistamab.

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Extracted eligibility criteria

Cancer type

Multiple Myeloma

Tumor Agnostic

Performance status

ROCKWOOD CLINICAL FRAILTY SCALE 0–5

Prior therapy

Min 3 prior lines

Must have received: proteasome inhibitor

Received at least 3 prior lines of therapy, including a proteasome inhibitor

Must have received: immunomodulatory agent

Received at least 3 prior lines of therapy, including ... an immunomodulatory agent

Must have received: anti-CD38 monoclonal antibody

Received at least 3 prior lines of therapy, including ... an anti-CD38 monoclonal antibody

Cannot have received: anti-BCMA therapy (teclistamab)

Prior or concurrent exposure to any of the following: Teclistamab or any anti-BCMA therapy

Cannot have received: other myeloma therapy (standard of care or investigational) including corticosteroids

Exception: within 3 days of first step-up dose of teclistamab

Other myeloma therapy (standard of care or investigational) including corticosteroids, within 3 days of first step-up dose of teclistamab

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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