OncoMatch/Clinical Trials/NCT06245330
A Phase I/II Study of AST-001 in Subjects With Advanced Solid Tumors
Is NCT06245330 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies AST-001 for solid tumor.
Treatment: AST-001 — A first-in-human open-label, Phase I/II study to evaluate the safety, tolerability, MTD/RP2D, PK, and preliminary efficacy of AST-001 administered as a single agent.
Check if I qualifyExtracted eligibility criteria
Cancer type
Tumor Agnostic
Pancreatic Cancer
Biomarker criteria
Required: AKR1C3 strongly positive expression (strongly positive)
Performance status
ECOG 0–1(Restricted strenuous activity)
Lab requirements
Blood counts
adequate bone marrow function
Kidney function
adequate renal function
Liver function
adequate liver function
An adequate renal, liver and bone marrow function.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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