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OncoMatch/Clinical Trials/NCT06243003

WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases

Is NCT06243003 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies non-drug interventions for sclc,extensive stage.

Phase 1/2RecruitingFudan UniversityNCT06243003Data as of May 2026

This study aims to evaluate the safety and efficacy of hippocampal-sparing WBRT combined with SRS as first-line treatment for SCLC patients with brain metastases.

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Extracted eligibility criteria

Cancer type

Small Cell Lung Cancer

Disease stage

Required: Stage IV

Metastatic disease required

Patients with initial diagnosis of ES-SCLC with brain metastases

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: any antitumor therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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